Interest areas

• Design and development of new chemical entities (NCEs) as anti-HIV and Antitubercular agents.
• Computer aided drug design
• Stability indicating method development using LC-MS
• Analytical and bio analytical method development of Active Pharmaceutical Ingredients (APIs)
• Impurity synthesis of API

Research

• Publications – 75 (International- 55, National-20)
• Presentations- 15 (International- 06, National- 9)
• Government-funded projects – 02
• Consultancy Project: 02
• Seed grant project :03
• Government fellowship – 1 (BOYSCAST Fellwship) Science and Engineering Research Board (SERB), Department of Science and Technology (DST)

Awards

• Recipient of BOYSCAST fellowship from Department of science and technology, New Delhi to carry out the research work St. John’s university New York.
• Recipient of Most Cited Research Article award 2003-2006 from Elsevier Ltd, Oxford, UK.,
• Received Junior Research Fellowship from Haffkine Institute for Training Research and Testing in the year 1998-2001.

Conferences/Workshops/Seminars attended

• Twelve conferences are attended including national and international.

Professional Memberships

• Association of Pharmaceutical Teachers of India (APTI) – Life Membership
• Indian Society of Technical Education
• Indian Pharmaceutical Association
• International congress of chemistry and environment

Recent Publications

• Merugu, S. R., Mokoena, S., Obakachi, V. A., Shaik, B. B., Kushawaha, B., Kushwaha, N. D., … Karpoormath, R. ,Bonde C. (2024). Novel 4,5-dibromo-N-phenyl-1H-pyrrole-2-carboxamide Hybrids as Promising DNA Gyrase Inhibitors: Design, synthesis and antimicrobial evaluation. Journal of Molecular Structure, 1302(137359), 137359. (IF 3.8)
• Al-Otaibi, J. S., Mary, Y. S., Mary, Y. S., Cheerlin Mishma, J. N., Gawad, J., & Bonde, C. (2024). DFT and AIM analysis of the interaction of amiloride (AM) drug with (Be/Ca-O)12 and Ag doped nanocages: A first principle study. Computational & Theoretical Chemistry, 1235(114556), 114556. (IF 2.3)
• Bhole, R. P., Kute, P., Chikhale, R. V., Bonde, C., Pant, A., & Gurav, S. (2023). Unlocking the Potential of PROTACs: A comprehensive review of protein degradation strategies in disease therapy. Bioorganic Chemistry, 139, 106720 (Impact Factor: 5.1)
• Bonde, C. G., Gawad, J., Bhole, R. P., Bonde, S. C., & Chikhale, R. V. (2023). Effective Drug Candidates against Global Pandemic of Novel Corona Virus (nCoV-2019): A Probability Check through Computational Approach for Public Health Emergency. Russian Journal of Bioorganic Chemistry, 1–7 (Impact Factor: 1.25)
• Shelke, M., Bonde, C., Deshpande, S., & Bhole, R. (2023). Drug Degradation Prediction, In Silico Toxicity Assessment and Development of Stability-Indicating, Quality by Design Enabled UFLC Method for Sacubitril-Valsartan. Russian Journal of Bioorganic Chemistry, 1–18. (Impact Factor: 1.25)
• Agrawal, R., Belemkar, S., & Bonde, C. (2023). A New Strategy for the Software-Assisted LC Separations of Ketoconazole and Its Impurities. Journal of Chromatographic Science, 61(5), 418–427 (Impact Factor: 1.3)
• Chaudhari, P. J., Bari, S. B., Surana, S. J., Shirkhedkar, A. A., Bonde, C. G., Khadse, S. C., … Cheke, R. S. (2022). Discovery and anticancer activity of novel 1, 3, 4-thiadiazole-and aziridine-based indolin-2-ones via in silico design followed by supramolecular green synthesis. ACS Omega, 7(20), 17270–17294.(IF 4.1)
• Bhole, R. P., Bonde C. et al. “Pharmacophore Model and Atom-Based 3D Quantitative Structure Activity Relationship (QSAR) of Human Immunodeficiency Virus-1 (HIV-1) Capsid Assembly Inhibitors.” Heliyon (2021) 7 (3), 1 (IF 4)
• Bhole, R. P., Bonde C. Chikhale R.et al. “Pharmacophore Model and Atom-Based 3D Quantitative Structure Activity Relationship (QSAR) of Human Immunodeficiency Virus-1 (HIV-1) Capsid Assembly Inhibitors.” Journal of Biomolecular Structure and Dynamics (2021) 7 (3), 1-9 (IF 5.2)
• Gawad, J., & Bonde, C.. Design, synthesis and biological evaluation of novel 6-(trifluoromethyl)-N-(4- oxothiazolidin-3-yl) quinazoline-2-carboxamide derivatives as a potential DprE1 inhibitors Journal of Molecular Structure, (2020) 1217, 128394. (IF 3.1)